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‘Very concerning’: the main medical groups react to Trump’s statement that Tylenol is linked to autism

The main medical organizations and scientific groups are reacting to the Trump administration statement on Monday that the use of acetaminophen during pregnancy, the main ingredient in the Tylenol medicine, may be related to autism, despite the limited evidence to suggest the association.

During a press conference at the White House, President Donald Trump said that the Food and Medicines Administration (FDA) will begin to notify the immediate doctors that “firmly recommends that women limit the use of Tylenol during pregnancy unless it is medically necessary” and that the FDA would update the tag for acetaminophen with improved information about the possible link.

In addition, Trump and Health Secretary and Human Services, Robert F. Kennedy Jr., suggested that the children’s vaccine schedule could contribute to autism, contradicting years of research that has not found any link between the two.

Some groups declared that acetaminophen is a safe medicine for pregnant women and that no study has found a direct cause and effect between use in pregnancy and autism.

Others said that vaccines have not been found to cause autism and that the vaccine schedule is safe.

In Tylenol

The American College of Obstetricians and Gynecologists (welcome) strongly rejected The statement that links acetaminophen in pregnancy with autism, describing it as “very worrying”, “irresponsible” and “not backed by the full body of scientific evidence.”

The group emphasized that more than 20 years of research do not show a link between the use of acetaminophen during pregnancy and autism, attention deficit disorder/hyperactivity or intellectual disability, specifically pointing to two high quality studies.

Tylenol packages are shown on a shelf in a CVS store, on September 22, 2025 in Greenbrae, California.

Justin Sullivan/Getty Images

“Acetaminophen is one of the few options available for pregnant patients to treat pain and fever, which can be harmful to pregnant people when they are not treated,” said Dr. Steven J. Fleischman, president of Vero, in a statement. “Maternal fever, headaches as an early sign of preeclampsia and pain are handled with the therapeutic use of acetaminophen, which makes acetaminopheno essential for people who need it.”

The statement continued: “The conditions that people use acetaminophen to treat during pregnancy are much more dangerous than any theoretical risk and can create severe morbidity and mortality for the pregnant person and the fetus.”

Similarly, the Maternal-Fetal Medicine Society (SMFM) reiterated A recommendation that acetaminophen is an “appropriate medication” to treat pain and fever during pregnancy.

The group also declared that pregnant people face risks when fever and pain are not treated.

“It is important to understand that not treated fever and pain during pregnancy carry significant risks for maternal and child health,” SMFM said in a statement. “Uncreated fever, particularly in the first quarter, increases the risk of spontaneous abortion, birth defects and premature delivery, and unrelated pain can cause maternal depression, high anxiety and blood pressure.”

In vaccines

The medical groups also reacted to the statements during the press conference that vaccines can cause autism, although many studies for decades did not find such a link.

Trump suggested during the press conference that Amish children do not receive vaccines and, therefore, do not receive autism diagnoses, despite Studies that have identified autism in Amish children and Not all Amish children are not vaccinated.

The American Academy of Pediatrics (AAP), the leading group of the nation that represents pediatricians, referred to claims as “dangerous” and forced to be confusing for parents.

“Studies have not repeatedly found any credible bond between children’s vaccines and autism that save life,” the group said in a statement. “This research, in many countries, which involves thousands of people, has covered multiple decades. Any effort to misrepresent sound, strong science raises a threat to children’s health.”

Trump also said Monday that children receive too many early shots in life, which seems to imply that children’s immune systems feel overwhelmed by vaccines.

Studies, like a 2018 study that involves about 1,000 American childrenThey have found that vaccines do not overwhelm or weaken the immune system and do not make children more susceptible to other infections.

“Pediatricians know firsthand that children’s immune systems work better after vaccination against serious and contagious diseases such as polyomyelitis, measles, ferine cough and hepatitis B,” said AAP. “Space or delay vaccines means that children will not have immunity against these diseases at the time they are more at risk.”

President Donald Trump accompanied by the Secretary of Health and Human Services Robert F. Kennedy Jr. and the Commissioner of the Food and Medicines Administration, Dr. Marty Makary, talks about autism in the White House in Washington, on September 22, 2025.

Andrew Harnik/Getty Images

In Leucovorin

The Trump administration also announced on Monday that the approval process was beginning for a medicine called Leucovorin as a possible treatment for autism.

Leucovorina, which is typically used as part of cancer attention, has demonstrated an early promise in a handful of small studies that suggest that it can help the symptoms of some children with autism, but experts warn that there is little evidence to support those statements.

The coalition of autism scientists He issued a statement Warning that it is too early to recommend leucovorin as a treatment.

The group said that there are some small trials that examine the use of the drug that are methodologically weak, use questionable statistical approaches and do not justify the clinical recommendations.

“The coalition of autism scientists reviewed these studies and discovered that researchers are not using high quality study designs or statistical analysis,” said the group.

The coalition requested a rigorous essay already a large scale with validated biomarkers and pre-registrated final points. The group also reaffirmed that vaccines are safe, they do not play any role in autism and that they undermine public health. The group requested that the Department of Health and Human Services invest in a high quality autism investigation and reviewed by pairs with independent supervision.

In addition, Autism Society of America (ASA) condemned the White House to promote what they say are “unfounded” statements about causes and treatments.

The group emphasized that autism is a complex and life condition without a single cause or cure, and that premature statements about acetaminophen or leucovorin ignore decades of rigorous investigations and risks to create false hopes and damages.

ASA said that research on high dose leukovorine is still in preliminary stages and that your safety should be understood before it is recommended for use among those with autism.

“Announce a cause or treatment without the rigorous and replicated science undermines trust and distracts from the critical work necessary for the community of Autism,” said the Board of Directors of the ASA in a statement. “What autistic people and their caregivers need are expanded services, inclusive policies and research that help improve the quality of life.”

Sony Salzman of ABC News contributed to this report.

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